We have used
antiparallel double crossover molecules as components
to create 2-D DNA crystals. In addition to producing
periodic arrays, we have also performed an algorithmic
assembly. We have used this
approach to organize DNAzymes and gold nanoparticles. In a major advance for nanorobotics, we have developed a cassette that can insert a sequence-dependent DNA
device into a 2D crystalline DNA array.
In another
advance using antiparallel double crossover molecules,
we have made a two-state nanomechanical device. We
have produced a robust sequence-dependent device. Further advances in nanomechanical devices are described in the link.
Future steps
in this project include the synthesis of 3-D crystalline arrays (lattices), and
exploring the relationship between order and symmetry.
Go to Seeman Lab DNA Nanotechnology Bibliography