Organizing Gold Nanoparticles with
We have used a robust DNA motif to organize two
different sizes of gold nanoparticles with DNA. The motif is shown below. Panel (a) is a schematic of the motif, and panel (b) shows a
This motif spans 3-space. The two helices in each direction can
be hooked together by double cohesion.
However, we have put sticky ends on only two of the directions, and the
third direction is used to house the gold nanoparticle.
The figure below shows how we can use two different
species of this motif to organize different arrangements of nanoparticles.
The TEM image below shows that we can actually
achieve these arrangements. The
image in (a) corresponds to the top
arrangement in (b) above, the image in (b) corresponds to the middle arrangement
above and the image in (c) corresponds to the bottom image in (b) above.
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