DNA Nanomechanical Devices

The goals of nanotechnology include nanorobotics. We have produced two different DNA nanomechanical devices. One device is based on the B-Z transition of DNA. Such a device can achieve two different structural states. A more complex device is a sequence dependent device. This device operates on the basis of differential hybridization topology. N such devices in an array could achieve 2**N different structural states. We have also learned how to control this device with RNA strands. We have used the sequence dependent device to build a translation device. In a major advance for DNA-based nanorobotics, we have developed a cassette that inserts the sequence-dependent device into a 2D crystalline DNA array.

We have developed a nanobot-like bipedal walking device, where the rise and fall of each foot of the biped is controlled by introducing DNA strands with specific sequences into the solution.

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