Four Topological Species

The left side of this synthetic scheme indicates the molecule from which the target products are produced. The four pairing regions, X and its complement X', Y and its complement Y' are indicated by the bulges from the square. The 3' end of the molecule is denoted by the arrowhead. The four independent solution conditions used to generate the target products are shown to the right of the basic structure. The pairing and helical handedness expected in each case is shown to the right of these conditions, and the molecular topology of the products is shown on the far right of the figure. The circle is shown in orange, the trefoil knot with negative nodes is shown in cyan, the amphicheiral figure-8 knot is shown in green, and the trefoil knot with positive nodes is shown in red. Up

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