PRESENTATION TOPICS

G25.1815

MACROMOLECULAR STRUCTURE

FALL 2003

INSTRUCTIONS FOR PRESENTATIONS:

 

[1]  EVERYBODY WILL HAVE A TOTAL OF 18 MINUTES.  PLEASE COME TO CLASS AS EARLY AS POSSIBLE, BECAUSE IF EVERYONE IS THERE WE CAN START.  WE WILL START WHEN EVERYONE IS THERE, OR 3:30, WHICHEVER COMES FIRST.

 

[2]       PLAN TO SPEND NO MORE THAN 13 MINUTES ON YOUR TALK.  THE REST OF THE TIME IS FOR DISCUSSION.  I WILL CUT YOU OFF AFTER 13 MINUTES.

 

[3]       YOU SHOULD USE GRAPHICS TO ILLUSTRATE THE IMPORTANT FIGURES AND POINTS IN THE PAPER.  THESE SHOULD BE DERIVED FROM THE ORIGINAL PUBLICATION.  IF FIGURES ARE IN COLOR IN THE ORIGINAL, YOUR OVERHEADS, IF YOU MAKE THEM, SHOULD BE IN COLOR, AS WELL.  START LOOKING FOR YOUR ARTICLES NOW.  IF THEY ARE HARD TO FIND IN THE E-JOURNALS AT BOBST, TELL ME.  IF YOU START PREPARING YOUR PRESENTATION THE NIGHT BEFORE YOUR TALK, YOU MAY HAVE ONLY GARBAGE TO SHOW.  IF YOU USE OVERHEADS, POINT ON THE SCREEN, NOT ON THE PROJECTOR.

 

[4]  EVERYBODY IS RESPONSIBLE FOR EVERY PAPER.  THAT IS WHY WE HAVE 5 MINUTES OF DISCUSSION SCHEDULED.  YOU WILL BE GRADED ON YOUR DISCUSSION PARTICIPATION.  EVERYBODY STARTS WITH A DISCUSSION GRADE OF 'C', A FAILING GRADE FOR A GRADUATE STUDENT.  HOWEVER, IF YOU ASK A DUMB QUESTION, INDICATING THAT YOU HAVE NOT READ THE ARTICLE, YOU WILL GET A GRADE BELOW 'C'.  GOOD QUESTIONS DO NOT REPEAT WHAT THE SPEAKER JUST SAID, BUT INVOLVE CLARIFICATION OF POINTS RAISED.  IF I AM UNSATISFIED WITH THE QUALITY OF DISCUSSION, I WILL GIVE A FINAL EXAM ON THE CONTENT OF THE PAPERS.  OTHERWISE I WON'T.

 

[5]  PRACTICE YOUR TALK AT LEAST 30 TIMES!!!

(1)       THURSDAY, DEC 02

Padlocked Oligonucleotides -- Chunhui Zhou

 

    1.     M. Bello-Roufal, T. Routon & C. EscudŽ, Ligand-mediated transcription elongation control using triples-based padlock oligonucleotides, Chem. & Biol. 11, 509-516 (2004).

 

(2)       THURSDAY, DEC 02

A Cubic DNA Crystal Structure  -- Justin Holub

 

    2.     N. Valls, I. Uson, C. Gouyette & J.A. Subirana, A cubic arrangement of DNA double helices based on nickel-guanine interactions, J. Am. Chem. Soc. 126, 7812-7816 (2004).

 

(3)       TUESDAY, DEC 02

DNA-Directed Chemistry (I) -- Sung Bin Shin

 

    3.     Z.J. Gartner, B.N. Tse, R. Grubina, J.B. Doyon, T.M. Snyder & D.R. Liu, DNA-Templated organic synthesis and selection of a library of macrocycles, Science 305, 1601-1605 (2004).

 

(4)       TUESDAY, DEC 02

DNA-Directed Chemistry (II) -- Chunhua Liu

 

    4.     Y. Chen & C. Mao, Reprogramming DNA-directed reactions on the basis of a DNA conformational change, J. Am. Chem. Soc. 126, 13240-13241 (2004).

 

(5)       THURSDAY, DEC 07

Autonomous DNA Motor -- Yan Li

 

    5.     Y. Chen & C. Mao, Putting a brake on an autonomous DNA nanomotor, J. Am. Chem. Soc. 126, 8626-8627 (2004).

 

(6)       THURSDAY, DEC 07

Replicable DNA Objects -- Jian Ren

 

    6.     W.M. Shih, J.D. Quispe & G.F. Joyce, A 1.7 kilobase single-stranded DNA that folds into a nanoscale octahedron, Nature 427, 618-621 (2004).

 

(7)       TUESDAY, DEC 07

Viral-Directed Gold Nanoparticle Scaffolding -- Zhang Lu

 

    7.     A.S. lum, C.M. Soto, C.D. Wilson, J.D. Cole, M. Kim, B. Gnade, A. Chatterji, W.F. Ochoa, T. Lin, J.E. Johnson & B.R. Ratna, Cowpea mosaic virus as a scaffold for #D patterning of gold nanoparticles, Nanolett. 4, 867-870 (2004).

 

(8)       TUESDAY, DEC 07

Viral-Directed Nanowire Assembly -- Xuling Zhu

 

    8.     C. Mao, D.J. Solis, R.D. Reiss, S.T. Kottmann, R.Y. Sweeney, A. Hayhurst, G.Georgiou, B. Iverson & A.M. Belcher, Virus-based toolkit for the directed synthesis of magnetic and semiconducting nanowires, Science 303, 213-217 (2004).

 

(9)       THURSDAY, DEC 09

Reprogramming the Genetic Code -- Hongzhou Gu

 

    9.     H. Murakami, D. Kourouklis & H. Suga, Using a solid-phase riboyme aminoacylation system to reprogram the genetic code,  Chem. & Biol. 10, 1077-1084 (2003).

 

(10)     THURSDAY, DEC 09

TectoRNA -- Jie Shao

 

  10.     B. Liu, S. Baudrey, L. Jaeger & G.C.Barzan, Characterization of tectoRNA assembly with cationic conjugated polymers, J. Am. Chem. Soc. 126, 4076-4077 (2004).

 

(11)     THURSDAY, DEC 09

Molecular Networks -- Dara Reeves

 

  11.     G. Ashkenasy, R. Jagasia, M. Yadav & M.R. Ghadiri, Design of a directed molecular network, Proc. Nat. Acad. Sci. (USA) 101, 10872-10877 (2004).

 

(12)     THURSDAY, DEC 09

Aptameric Sensors -- Harikrishnan Swamy

 

  12.     M.N. Stojanovic & D. M. Kolpashchikov,, Modular aptameric sensors J. Am. Chem. Soc. 126, 9266-9270 (2004).